The 2023 Cleveland Open was a professional tennis tournament played on indoor hard courts. It was the fifth edition of the tournament which was part of the 2023 ATP Challenger Tour. It took place in Cleveland, Ohio, United States between January 30 and February 5, 2023.

Country	Player	Rank1	Seed
ECU	Emilio Gómez	101	1
CHN	Wu Yibing	114	2
USA	Steve Johnson	119	3
USA	Jack Sock	129	4
USA	Aleksandar Kovacevic	163	5
USA	Stefan Kozlov	199	6
USA	Brandon Holt	215	7
CAN	Gabriel Diallo	223	8

• ¹ Rankings are as of January 16, 2023.^[1]

The following players received wildcards into the singles main draw:

• Stefan Kozlov
• Alex Michelsen
• Jack Pinnington Jones

The following player received entry into the singles main draw as an alternate:

• Patrick Kypson

The following players received entry from the qualifying draw:

• Jaimee Floyd Angele
• Ryan Harrison
• Toby Kodat
• Aidan Mayo
• Matija Pecotić
• Alfredo Perez

• Aleksandar Kovacevic def. Wu Yibing 3–6, 7–5, 7–6^(7–2).

• Robert Galloway / Hans Hach Verdugo def. Ruben Gonzales / Reese Stalder 3–6, 7–5, [10–6].