Fabio Fognini defeated Dušan Lajović in the final, 6–3, 6–4 to win the singles tennis title at the 2019 Monte-Carlo Masters. It was his first ATP Tour Masters 1000 title.

Rafael Nadal was the three-time defending champion,^[1] but lost in the semifinals to Fognini.

The top eight seeds receive a bye into the second round.

Click on the seed number of a player to go to their draw section.

	Quarterfinals							Semifinals							Final
	1	Novak Djokovic	3	6	2
	10	Daniil Medvedev	6	4	6
								10	Daniil Medvedev	5	1
									Dušan Lajović	7	6
		Dušan Lajović	6	7
	Q	Lorenzo Sonego	4	5
																Dušan Lajović	3	4
															13	Fabio Fognini	6	6
	9	Borna Ćorić	6	3	2
	13	Fabio Fognini	1	6	6
								13	Fabio Fognini	6	6
								2	Rafael Nadal	4	2
		Guido Pella	61	3
	2	Rafael Nadal	77	6

	First round							Second round							Third round							Quarterfinals
								1	N Djokovic	6	4	6
	LL	T Daniel	1	3					P Kohlschreiber	3	6	4
		P Kohlschreiber	6	6											1	N Djokovic	6	6
	PR	J-W Tsonga	4	0r												T Fritz	3	0
		T Fritz	6	2					T Fritz	6	6
		D Schwartzman	4	6	6				D Schwartzman	4	2
	17	K Edmund	6	3	1																	1	N Djokovic	3	6	2
	10	D Medvedev	6	6																		10	D Medvedev	6	4	6
		J Sousa	1	1				10	D Medvedev	6	6
	Q	A Bedene	4	2					R Albot	1	2
		R Albot	6	6											10	D Medvedev	6	1	6
		J Chardy	3	4											6	S Tsitsipas	2	6	4
		M Kukushkin	6	6					M Kukushkin	3	5
								6	S Tsitsipas	6	7

	First round							Second round							Third round							Quarterfinals
								4	D Thiem	6	6
	Q	F Delbonis	63	5					M Kližan	1	4
		M Kližan	77	7											4	D Thiem	3	3
	Alt	M Jaziri	4	4												D Lajović	6	6
		D Lajović	6	6					D Lajović	6	6
	Q	G Andreozzi	1	4				16	D Goffin	3	4
	16	D Goffin	6	6																			D Lajović	6	7
	12	N Basilashvili	5	6	1																	Q	L Sonego	4	5
		M Fucsovics	7	3	6				M Fucsovics	63	3
		A Mannarino	4	3					C Norrie	77	6
		C Norrie	6	6												C Norrie	2	5
		A Seppi	64	4											Q	L Sonego	6	7
	Q	L Sonego	77	6				Q	L Sonego	77	6
								8	K Khachanov	64	4

	First round							Second round							Third round							Quarterfinals
								5	K Nishikori	5	4
		F Verdasco	4	4					P-H Herbert	7	6
		P-H Herbert	6	6												P-H Herbert	4	2
	WC	L Catarina	0	3											9	B Ćorić	6	6
	WC	J Munar	6	6				WC	J Munar	77	67	4
		H Hurkacz	4	7	5			9	B Ćorić	63	79	6
	9	B Ćorić	6	5	7																	9	B Ćorić	6	3	2
	13	F Fognini	4	7	6																	13	F Fognini	1	6	6
	Q	A Rublev	6	5	4			13	F Fognini	w/o
		G Simon	7	6					G Simon
	Q	A Popyrin	5	1											13	F Fognini	78	6
	WC	F Auger-Aliassime	7	77											3	A Zverev	66	1
	Q	JI Londero	5	65				WC	F Auger-Aliassime	1	4
								3	A Zverev	6	6

	First round							Second round							Third round							Quarterfinals
								7	M Čilić	3	7	1
		L Đere	77	2	4				G Pella	6	5	6
		G Pella	62	6	6											G Pella	6	4	6
		L Pouille	5	3											11	M Cecchinato	4	6	4
		S Wawrinka	7	6					S Wawrinka	6	5	3
		D Džumhur	0r					11	M Cecchinato	0	7	6
	11	M Cecchinato	4																				G Pella	61	3
	15	D Shapovalov	7	3	1																	2	R Nadal	77	6
		J-L Struff	5	6	6				J-L Struff	62	4
		M Berrettini	5	4					G Dimitrov	77	6
		G Dimitrov	7	6												G Dimitrov	4	1
		R Bautista Agut	3	6	6										2	R Nadal	6	6
		J Millman	6	1	1				R Bautista Agut	1	1
								2	R Nadal	6	6

1. Taro Daniel

	First round							Qualifying competition
	1	Leonardo Mayer	65	6	62
		Alexei Popyrin	77	2	77
									Alexei Popyrin	6	77
									Elias Ymer	3	62
		Elias Ymer	6	6
	14	Miomir Kecmanović	1	3

	First round							Qualifying competition
	2	Ugo Humbert	3	7	6
	WC	Florent Diep	6	5	3
								2	Ugo Humbert	4	4
									Andrey Rublev	6	6
		Andrey Rublev	4	77	78
	10	Bernard Tomic	6	65	66

	First round							Qualifying competition
	3	Yoshihito Nishioka	2	6	0
		Lorenzo Sonego	6	4	6
									Lorenzo Sonego	w/o
									Marco Trungelliti
		Marco Trungelliti	6	6
	12	Peter Gojowczyk	4	2

	First round							Qualifying competition
	4	Juan Ignacio Londero	6	6
	WC	Romain Arneodo	0	4
								4	Juan Ignacio Londero	6	6
									Thomas Fabbiano	4	1
		Thomas Fabbiano	3	6	6
	13	Feliciano López	6	4	2

	First round							Qualifying competition
	5	Aljaž Bedene	6	6
	WC	Hugo Nys	2	4
								5	Aljaž Bedene	77	6
								8	Taro Daniel	65	3
		Yannick Maden	4	4
	8	Taro Daniel	6	6

	First round							Qualifying competition
	6	Mischa Zverev	62	64
	WC	Julian Ocleppo	77	77
								WC	Julian Ocleppo	3	1
									Guido Andreozzi	6	6
		Guido Andreozzi	6	6
	9	Ernests Gulbis	4	1

	First round							Qualifying competition
	7	Federico Delbonis	6	3
		Ilya Ivashka	2	4r
								7	Federico Delbonis	7	6
								11	Albert Ramos Viñolas	5	0
		Maximilian Marterer	2	2
	11	Albert Ramos Viñolas	6	6

• Main draw
• Qualifying draw