The 2012 Charlottesville Men's Pro Challenger was a professional tennis tournament played on hard courts. It was the fourth edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Charlottesville, United States between October 29 and November 4, 2012.

Country	Player	Rank1	Seed
USA	Jesse Levine	69	1
RUS	Alex Bogomolov Jr.	96	2
USA	Michael Russell	102	3
GER	Mischa Zverev	140	4
USA	Ryan Sweeting	146	5
USA	Bobby Reynolds	152	6
USA	Tim Smyczek	158	7
USA	Denis Kudla	162	8

• ¹ Rankings are as of October 22, 2012.

The following players received wildcards into the singles main draw:

• Somdev Devvarman
• Alexander Domijan
• Austin Krajicek
• Michael McClune

The following players received entry from the qualifying draw:

• Taro Daniel
• Eric Quigley
• Mac Styslinger
• Fritz Wolmarans

• Denis Kudla def. Alex Kuznetsov, 6–0, 6–3

• John Peers / John-Patrick Smith def. Jarmere Jenkins / Jack Sock, 7–5, 6–1

• Official Website