1-Bromododecane is a bromoalkane with the formula Br(CH2)11CH3. It is a colorless liquid. It is used as a long chain alkylating agent to improve the lipophilicity and hydrophobicity of organic molecules for biological applications.[2]

Production

Most 1-bromoalkanes are prepared by free-radical addition of hydrogen bromide to the 1-alkene, which is 1-dodecene in the case of 1-bromododecane. These conditions lead to anti-Markovnikov addition, giving the 1-bromo derivative.[2]

1-Bromododecane can also be prepared by treating dodecanol with hydrobromic acid and sulfuric acid.[3]

CH3(CH2)11OH + HBr → CH3(CH2)11Br + H2O

References

  1. ^ "1-BROMODODECANE - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification. Retrieved 4 December 2019.
  2. ^ a b Dagani, M. J.; Barda, H. J.; Benya, T. J.; Sanders, D. C. "Bromine Compounds". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a04_405. ISBN 978-3-527-30673-2.
  3. ^ Organicum. Practical Handbook of Organic Chemistry, by Heinz Becker, Werner Berger and Günter Domschke, Addison-Wesley Pub. Co, 195-196, (1973)
Allikas: https://en.wikipedia.org/wiki/1-bromododecane
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