Vermistatin is an organic compound and a metabolite of mine-dwelling Penicillium vermiculatum found in Berkeley Pit Lake, Butte, Montana.[1] Penisimplicissin is a vermistatin analog with anticancer activity.[2]

References

  1. ^ Fuska, J; Uhrín, D; Proksa, B; Votický, Z; Ruppeldt, J (1986). "The structure of vermistatin, a new metabolite from Penicillium vermiculatum". The Journal of Antibiotics. 39 (11): 1605–8. doi:10.7164/antibiotics.39.1605. PMID 3793630.
  2. ^ Stierle AA, Stierle DB, Girtsman T (2012). "Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines". J Nat Prod. 75 (3): 344–50. doi:10.1021/np200414c. PMC 3330824. PMID 22295871.


Allikas: https://en.wikipedia.org/wiki/Vermistatin
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