Hydroxymalonate dehydrogenase

hydroxymalonate dehydrogenase
Identifiers
EC no.1.1.1.167
CAS no.58693-60-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a hydroxymalonate dehydrogenase (EC 1.1.1.167) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H+
 
 

The two substrates of this enzyme are tartronic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are mesoxalic acid, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydroxymalonate:NAD+ oxidoreductase.

References

  1. ^ Enzyme 1.1.1.167 at KEGG Pathway Database.
  2. ^ Jukova NI, Klunova SM, Philippovich YB (1971). Biochemistry of Insects (17). Moscow: V.I. Lenin State Pedagogical Institute: 56. {{cite journal}}: Missing or empty |title= (help)