Events from the year 1564 in art.

• February 18 – Michelangelo dies aged 88 in Rome leaving the Rondanini Pietà unfinished.

• Pieter Bruegel the Elder
  • The Adoration of the Kings
  • The Procession to Calvary

• June 11 - Joseph Heintz the Elder, Swiss painter, draftsman and architect (died 1609)
• September 13 - Vincenzo Giustiniani, art collector, patron of Caravaggio (died 1637)
• November - Francisco Pacheco, Spanish painter and writer on painting (died 1644)
• date unknown
  • Zeng Jing, Chinese painter during the Ming Dynasty (died 1647)
  • Bartolomé González y Serrano, Spanish Baroque portrait painter (died 1627)
  • Hans Rottenhammer, German painter (died 1625)
• probable
  • Pieter Brueghel the Younger, Flemish Renaissance painter (died 1636)
  • Crispijn van de Passe the Elder, Dutch publisher and engraver (died 1637)

• February 18 – Michelangelo, Italian Renaissance sculptor, painter, architect and poet (born 1475)
• date unknown
  • Domenico Campagnola, Italian painter and engraver of the Renaissance period (born c.1500); he was a pupil of his father, the painter Giulio Campagnola.
  • Cesare da Bagno, Italian sculptor and medallist (born 1530)
  • Jakob Woller, German sculptor (born 1510)