RDX is an explosive.
RDX may also refer to:
Science and technology
- Radixin, a protein encoded by the RDX gene
- RDX register, a CPU register in 64-bit x86 processors
- RDX Technology, a data storage format
Other uses
- RDX (band), a reggae duo from Kingston, Jamaica
- Acura RDX, a 2006–present Japanese compact SUV
- RDX Love, a 2019 Indian Telugu-language film directed by Shankar Bhanu
- RDX: Robert Dony Xavier, a 2023 Indian Malayalam-language film directed by Nahas Hidayath
- Ranvir Dhanraj Xaja "RDX Bhai", fictional criminal played by Feroz Khan in the 2007 Indian film Welcome
- Reaction Dynamics (company), a space company