Bernice is a given name.

Some notable individuals with the name include:

• Berenice (daughter of Herod Agrippa I) (28 AD–?), spelled "Bernice" in the New Testament
• Bernice Pauahi Bishop (1831–1884), a Hawaiian princess
• Bernice Bonello, Maltese politician
• Bernice Coppieters (born 1970), Belgian ballet dancer
• Bernice Gera (1931–1992), the first female umpire in professional baseball
• Bernice Goodman (1927–2003), American social worker, gay rights activist
• Bernice Gottlieb (born 1931), early leader in the trans-racial adoption movement
• Bernice Kentner (1929–2018), American cosmetologist and author
• Bernice King (born 1963), Baptist minister and daughter of Dr. Martin Luther King
• Bernice Neugarten (1916–2001), professor and researcher in the field of aging
• Bernice Petkere (1901–2000), American songwriter dubbed the "Queen of Tin Pan Alley" by Irving Berlin
• Bernice Rubens (1928–2004), Booker Prize-winning Welsh novelist
• Bernice F. Sisk (1910–1995), American Democratic Congressman from California
• Sydney Bernice Sweeney (born 1997), American actress

• Bernice, Bert's pet pigeon from the children's television series Sesame Street
• Bernice, a reality television character in the truTV series South Beach Tow, played by Lakatriona Brunson
• Bernice Blackstock, from the British soap opera Emmerdale
• Bernice Clasky, in the Adam Sandler movie "Spanglish"
• Bernice Clifton, in the TV series Designing Women
• Bernice Fish, in the TV series Fish
• Bernice Halper, the title character's best friend in the Luann comic strip
• Bernice Hibbert, a recurring character on The Simpsons TV show
• Bernice Summerfield, a companion of the seventh Dr. Who in novels
• Bernice Waverley, in the Australian TV drama series City Homicide
• Bernice the Whiffle Hen in Popeye the Sailor

• Bernice (disambiguation)