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A department within CHOP. Andrew nyr (talk, contribs) 19:43, 30 April 2020 (UTC)[reply]

COI edit requests

Hi! I'm a COI editor for CHOP, a client of my employer, Porter Novelli. Requesting some updates to this article:

  • In the infobox, lead, and at the beginning of "Facilities", update the number of beds from 594 to 692.[1] (I know primary sources are sometimes acceptable for certain fundamental info; if an independent source is required, Becker's Hospital Review has an older (but still more recent than the currently used) figure of 667.[2])
  • In the lead, delete "on the campus of the University of Pennsylvania". This is inaccurate; the assertion two paragraphs later that "The hospital is located next to the University of Pennsylvania" is correct. ("Fourth hospital, since 1974" in "History" also confirms this.)
  • In the lead, update
more than one million outpatient and inpatient visits annually.[3]
to
more than 1.6 million outpatient and inpatient visits annually.[1]
  • Also in the lead, update
CHOP has been ranked as the best children's hospital in the United States by U.S. News & World Report[4] and Parents Magazine[5] since 2020. As of 2020, it was ranked number one in the nation by U.S. News & World Report for three out of ten specialties.[6]
to
CHOP has been ranked as one of the best children's hospitals in the United States by U.S. News & World Report since 2007.[7][8] As of 2024, it was ranked number one in the nation by U.S. News & World Report for two out of 11 specialties.[9]
I suggest cutting the Parents Magazine ranking, since the publication no longer ranks children's hospitals.
  • Add to end of lead:
CHOP has 19,722 employees[1] and reported $4.54 billion in revenue in fiscal year 2024.[10]
  • The subsections of the "History" section use the word "hospital" in a confusing way – first hospital, second hospital, etc. – implying there are several hospitals. I suggest changing "hospital" to "location" in each of these titles.
  • Rename the last subsection of "History" to "Fourth location 1974–2015" and split the last two paragraphs of "History" into a new subsection, "Area expansion, since 2015".
  • In the penultimate paragraph of "History", delete
Later that year, in October 2015, the expansion of the Brandywine Valley Specialty Care and Ambulatory Surgery Center was opened. This is a 44,000-square-foot (4,100 m2) expansion.[11]
This is a pretty minor expansion; mentioning it seems WP:UNDUE.
  • Add to end of "History":
In January 2022, CHOP opened a new inpatient hospital on its King of Prussia campus,[12] followed by a new Center for Advanced Behavioral Healthcare in West Philadelphia in October 2022[13] and a Behavioral Health and Crisis Center in spring 2024.[14][15] The hospital also opened new satellite locations in New Brunswick and Cape May, among others.[16]
  • In "Facilities", update
Each year the hospital admits more than 28,000 children and more than 1.167 million are seen in the emergency and outpatient departments.[17]
to
Each year the hospital admits more than 34,000 patients and more than 1.6 million are seen in the emergency and outpatient departments.[1] In addition to the facilities below, CHOP operates satellite locations in New Brunswick and Cape May, New Jersey, and Lancaster, Pennsylvania.[18]
  • Add to end of "Expansion plans" in "Facilities":
The second building, the Morgan Center for Research and Innovation, is a 17-story, 350,000-square-foot facility to provide more laboratory research capacity for molecular and biomedical studies. It began construction in 2022 and is scheduled to open in 2025.[19]
  • Add new subsections to "Facilities":
Center for Advanced Behavioral Health Care
CHOP opened a mental health center in West Philadelphia in October 2022. The facility is located at at 46th and Market,[13] with an address of 4601 Market St. The 47,000-square-foot facility was opened in response to rising demand due to gun violence and the COVID-19 pandemic, among other factors.[20][21]
Behavioral Health and Crisis Center
CHOP's Behavioral Health and Crisis Center, located on Cedar Avenue in West Philadelphia, is a pediatric inpatient behavioral health facility with a walk-in crisis center.[14][15]
  • Add to end of "Services":
CHOP has also explored holistic treatment programs, particularly for mental health. In 2022, the hospital collaborated with Let’s Go Outdoors, Awbury Arboretum, and the U.S. Forest Service to create Prescribe Outside, a program encouraging children and their families to spend time outdoors as a form of preventative healthcare.[22] This was a follow-up to a similar program, NaturePHL, launched in 2017.[23][24]
CHOP is one of a few U.S. children's hospitals that can perform complicated fetal surgeries.[25] The hospital established its Center for Fetal Diagnosis and Treatment in 1995;[26] in 2021, its 2,000th fetal surgery patient was born.[27] CHOP also performs surgeries to separate conjoined twins.[28] From 1957 to 2024, the hospital has completed 32 conjoined twin separations, more than any other North American hospital.[29]
The National Institutes of Health selected CHOP to join the Undiagnosed Diseases Network in 2018, providing research grants and including CHOP in a study on advanced genetic testing.[30] CHOP has used an "ultra deep" type of genetic testing to support diagnosis of rare diseases.[31][32] The Advanced Research Projects Agency for Health gave CHOP a $10 million grant in October 2024 to implement Real-time Analysis and Discovery in Integrated And Networked Technologies (RADIANT), a tool to gather and share data on rare childhood diseases from electronic health records of patients around the U.S. in real time.[33]
As of June 2024, CHOP was running 11 remote management programs with capacity to monitor 11,000 patients, a tactic that is usually more common in adult than pediatric care.[34]
  • Add to end of "Research" (which should maybe be a top-level section?):
CHOP led the 2011 Management of Myelomeningocele Study, which was first to demonstrate that fetal surgery for spina bifida could offer more benefits than repair after birth.[27] CHOP also participated in a follow-up study, conducted between 2011 and 2017 and published in 2021, that confirmed the benefits continued into patients' school years.[35][27]
In 2016, CHOP's Center for Autism Research joined the Simons Foundation Autism Research Initiative's study on genetics and autism,[36] the largest autism study in the history of the U.S.[37]
Several CHOP doctors published a 2021 study in the Journal of the American Academy of Child and Adolescent Psychiatry comparing rates of attempted suicide among Black American pre-adolescent and their white peers, linking the increase for Black youths to exposure to discrimination.[38][39]
  • Add a subsection to "Research":
Cell and gene therapies
In 2012, CHOP treated a child with leukemia using CAR T cell therapy, making her the first child cured of cancer using this therapy.[40]
From 2008 to 2018, CHOP participated in 30 clinical trials for cell and gene therapies, creating products for hundreds of patients.[41] In October 2018, CHOP opened a 15,000-square-foot, $75 million clinical manufacturing facility focused on testing cell and gene therapies and producing viral vectors to deliver them.[42] The facility more than doubles the hospital's production capacity and reduces cost per treatment. The facility is located in the basement of the Colket Translational Research Building in University City.[41] The next year, CHOP scientists announced in Nature Communications that they had developed a sensitive screening method for adeno-associated virus vectors.[43]
In 2021, CHOP conducted a study on Casgevy, a gene therapy treatment using CRISPR to treat sickle cell disease. Casgevy received FDA approval in December 2023, making it the first gene therapy to treat sickle cell disease approved by the Food and Drug Administration.[44] By August 2024, CHOP had provided gene therapy to its first sickle cell patient outside of a research setting.[45]
CHOP research also played a role in the development of two other FDA-approved gene therapies, Kymriah for leukemia (approved in August 2017[46]) and Luxturna for an inherited blindness (approved in December 2017[47]).[41] Luxturna is produced by Spark Therapeutics, which spun off from CHOP in 2013.[42]
In 2023, the hospital acquired a machine to support the production of CAR T cell therapies faster and at lower cost.[48] By November 2023, CHOP had treated more than 500 children and hundreds more adults with CAR T therapy.[49] The hospital conducted research finding that children with acute lymphoblastic leukemia from low-income households receive similar benefit from these therapies as children from more advantaged households.[50] CHOP has also collaborated with the Stanford University School of Medicine on research explaining how CAR T therapies work and how to improve them.[51]
In January 2024, CHOP announced that it had allowed an 11-year-old boy who was born deaf in both ears due to the OTOF gene[52] to hear for the first time using an experimental gene therapy treatment, marking the first time gene therapy was used as a treatment for hereditary hearing loss in the U.S.[53]
  • In "Awards", add after (or replace?) "In 2021 the hospital was ranked as the No. 2 best children's hospital in the United States by U.S. News & World Report on the publications' honor roll list.[54]":
In its 2024–2025 rankings, U.S. News & World Report included CHOP on its unranked "honor roll" of the best children's hospitals[55] and named it the #1 children's hospital in the Mid-Atlantic region.[56]
  • In "Awards", update
U.S. News & World Report Rankings for Children's Hospital of Philadelphia[57]
Specialty Rank (In the U.S.) Score (Out of 100)
Neonatology 3 91.7
Pediatric Cancer 7 94.7
Pediatric Cardiology & Heart Surgery 7 80.0
Pediatric Diabetes & Endocrinology 1 100.0
Pediatric Gastroenterology & GI Surgery 1 100.0
Pediatric Nephrology 4 96.2
Pediatric Neurology & Neurosurgery 2 98.6
Pediatric Orthopedics 3 95.4
Pediatric Pulmonology & Lung Surgery 2 98.2
Pediatric Urology 2 96.5
to
2024–2025 U.S. News & World Report Rankings for Children's Hospital of Philadelphia[57]
Specialty Rank (In the U.S.) Score (Out of 100)
Neonatology 4 89.9
Pediatric Cancer 3 95.6
Pediatric Cardiology & Heart Surgery 18 75.9
Pediatric Diabetes & Endocrinology 1 100.0
Pediatric Gastroenterology & GI Surgery 3 98.7
Pediatric Nephrology 6 95.5
Pediatric Neurology & Neurosurgery 4 97.5
Pediatric Orthopedics 1 100.0
Pediatric Pulmonology & Lung Surgery 3 96.2
Pediatric Urology 3 90.8
Sources

  1. ^ a b c d "Hospital and CHOP Care Network Statistics". The Children's Hospital of Philadelphia. Retrieved March 3, 2025.
  2. ^ Gamble, Molly (February 14, 2024). "30 largest children's hospitals". Becker's Hospital Review. Retrieved August 8, 2024.
  3. ^ Smathers, Sarah A.; Sammons, Julia S. (2020). "A strategy for expanding infection prevention resources to support organizational growth". American Journal of Infection Control. 48 (9): 975–981. doi:10.1016/j.ajic.2020.04.008. PMID 32305429. S2CID 216031522.
  4. ^ "Children's Hospital of Philadelphia in Philadelphia, PA – Rankings, Ratings & Photos | US News Best Children's Hospitals Rankings". 2020-02-14. Archived from the original on 2020-02-14. Retrieved 2020-02-14.
  5. ^ "20 Top Children's Hospitals in Innovation and Technology". Parents. Archived from the original on 2020-06-19. Retrieved 2020-02-14.
  6. ^ "Best Children's Hospitals: General Pediatrics" Archived 2012-06-01 at the Wayback Machine U.S. News & World Report, Accessed 9 June 2012.
  7. ^ Hitti, Miranda (August 27, 2007). "Philadelphia Children's Hospital Tops List". CBS News. Retrieved December 24, 2024.
  8. ^ George, John (October 8, 2024). "CHOP once again ranks among 10 best children's hospitals in the nation, according to U.S. News". Philadelphia Business Journal. Retrieved January 14, 2025.
  9. ^ "Children's Hospital of Philadelphia in Philadelphia, PA - Rankings & Ratings". U.S. News & World Report. Retrieved January 14, 2025.
  10. ^ Brubaker, Harold (November 7, 2024). "Most Philadelphia nonprofit health systems had improved financial results in fiscal 2024". The Philadelphia Inquirer. Retrieved March 3, 2025.
  11. ^ Dyrda, Laura. "Children's Hospital of Philadelphia opens Brandywine Valley Specialty Care and ASC: 5 things to know". Beckersasc.com. Archived from the original on 2015-10-08. Retrieved 2015-10-29.
  12. ^ Yu, Alan (January 26, 2022). "New children's hospital opens in King of Prussia". WHYY. Retrieved August 8, 2024.
  13. ^ a b Stahl, Stephanie (October 27, 2022). "CHOP opens new mental health center in West Philadelphia". CBS Philadelphia. Retrieved August 8, 2024.
  14. ^ a b Brubaker, Harold (June 5, 2024). "Philadelphia-area health systems had strong revenue growth for the first nine months of fiscal 2024". The Philadelphia Inquirer. Retrieved March 3, 2025.
  15. ^ a b "New CHOP Facility Expands Mental Health Crisis and Inpatient Care in Philadelphia". The Children's Hospital of Philadelphia. March 6, 2024. Retrieved March 3, 2025.
  16. ^ Toussaint, Jensen (May 18, 2024). "Children's Hospital of Philadelphia Continues To Thrive Under Madeline Bell's Leadership". PHILADELPHIA.Today. Retrieved August 7, 2024.
  17. ^ "Children's Hospital of Philadelphia 2010 – 11 Annual Report" (PDF). CHOP. 2011. Archived from the original (PDF) on April 27, 2011. Retrieved June 9, 2012.
  18. ^ Bradley, Michael (May 2, 2024). "Madeline Bell Leads the Way at Children's Hospital of Philadelphia". Main Line Today. Retrieved August 8, 2024.
  19. ^ Brubaker, Harold (May 14, 2024). "CHOP got a $50 million gift from Mitchell Morgan and his family for its new research building". The Philadelphia Inquirer. Retrieved March 3, 2025.
  20. ^ Gutman, Abraham (August 26, 2022). "CHOP has a new mental health center in West Philly. Community members want providers to spend time outside its walls". The Philadelphia Inquirer. Retrieved August 8, 2024.
  21. ^ Larson, Alec (October 27, 2022). "CHOP opens behavioral health center in West Philly". The Philadelphia Tribune. Retrieved August 8, 2024.
  22. ^ Adams, Kiersten (December 1, 2023). "Time in nature is a boon for children's physical and mental health. It's also great for parents". Grid Magazine. Retrieved August 21, 2024.
  23. ^ Fisher, Adjua (July 24, 2017). "CHOP Docs Will Start Prescribing What This Summer?". Philadelphia Magazine. Retrieved August 21, 2024.
  24. ^ Weilbacher, Mike (December 9, 2016). "NATURAL SELECTIONS: CHOP's Barbara Rolnick champions NaturePHL to fight 'depression epidemic'". The Times Herald. Retrieved August 21, 2024.
  25. ^ Holohan, Meghan (November 6, 2024). "EXCLUSIVE: 'Waiting for her to die': Baby with tumor on heart in the womb saved by rare surgery". TODAY.com. Retrieved January 14, 2025.
  26. ^ Jones, Ayana (June 11, 2013). "CHOP performs 1,000th fetal surgery". The Philadelphia Tribune. Retrieved January 14, 2025.
  27. ^ a b c Romero, Tracey (June 22, 2021). "CHOP milestone exemplifies three decades of progress in fetal surgery". PhillyVoice. Retrieved January 14, 2025.
  28. ^ "Twin boys born conjoined celebrate 1st birthday after separation surgery". AP News. October 9, 2024. Retrieved January 14, 2025.
  29. ^ Lynch, Cherise (October 9, 2024). "CHOP surgeons successfully separate conjoined twin boys after 8-hour surgery". NBC10 Philadelphia. Retrieved January 14, 2025.
  30. ^ O'Brien, Amanda (October 1, 2018). "HUP and CHOP join Undiagnosed Diseases Network to study rare disorders". The Daily Pennsylvanian. Retrieved January 14, 2025.
  31. ^ Avril, Tom (July 29, 2023). "At CHOP, 'ultra-deep' genetic testing detects rare mutations that cause debilitating childhood diseases". The Philadelphia Inquirer. Retrieved January 14, 2025.
  32. ^ Ellison, Katherine (August 5, 2024). "When a child is mysteriously and seriously ill, here are places to turn". Washington Post. Retrieved January 14, 2025.
  33. ^ McCook, Alison (October 16, 2024). "CHOP gets $10 million for tool to transform care for kids with rare diseases". The Philadelphia Inquirer. Retrieved January 14, 2025.
  34. ^ Bruce, Giles (June 13, 2024). "How 1 hospital bucked a remote patient monitoring trend". Becker's Hospital Review. Retrieved January 14, 2025.
  35. ^ Gantz, Sarah (January 24, 2020). "Children's Hospital of Philadelphia finds benefits of fetal surgery for spina bifida continue years later". The Philadelphia Inquirer. Retrieved January 14, 2025.
  36. ^ George, John (April 29, 2016). "CHOP joins 'largest ever' autism genetics study". Philadelphia Business Journal. Retrieved August 8, 2024.
  37. ^ Craig, Daniel (April 29, 2016). "CHOP joining country's largest autism study". PhillyVoice. Retrieved August 8, 2024.
  38. ^ Gutman, Abraham (June 21, 2022). "CHOP's only psychiatrist for infants is worried about the mental health of Philadelphia's youngest". The Philadelphia Inquirer. Retrieved August 21, 2024.
  39. ^ Argabright, Stirling T.; Visoki, Elina; Moore, Tyler M.; Ryan, Dallas T.; DiDomenico, Grace E.; Njoroge, Wanjikũ F.M.; Taylor, Jerome H.; Guloksuz, Sinan; Gur, Ruben C.; Gur, Raquel E.; Benton, Tami D.; Barzilay, Ran (2022). "Association Between Discrimination Stress and Suicidality in Preadolescent Children". Journal of the American Academy of Child & Adolescent Psychiatry. 61 (5): 686–697. doi:10.1016/j.jaac.2021.08.011. PMC 8917360. PMID 34425231.
  40. ^ Gantz, Sarah (October 30, 2023). "Emily Whitehead was the first child cured of cancer with therapy from Penn. She's back as a freshman". The Philadelphia Inquirer. Retrieved August 8, 2024.
  41. ^ a b c DiStefano, Joseph N. (November 1, 2018). "CHOP set to open its gene-therapy factory". The Philadelphia Inquirer. Retrieved August 21, 2024.
  42. ^ a b George, John (November 1, 2018). "Gene therapy: CHOP unveils $75M manufacturing facility (Photos)". Philadelphia Business Journal. Retrieved August 21, 2024.
  43. ^ "Gene Therapy Vectors Deliver to More Places Than Once Thought". GEN - Genetic Engineering and Biotechnology News. July 31, 2019. Retrieved August 22, 2024.
  44. ^ Avril, Tom (December 8, 2023). "The FDA just approved the first gene-editing treatment, and CHOP played a key role". The Philadelphia Inquirer. Retrieved August 21, 2024.
  45. ^ Stahl, Stephanie; Nau, Brad (September 11, 2024). "New Jersey college student suffering from sickle cell disease has newfound hope with gene therapy at CHOP - CBS Philadelphia". CBS Philadelphia. Retrieved January 14, 2025.
  46. ^ Schweigert, Keith (August 31, 2017). "FDA approves new gene therapy treatment for leukemia developed by Penn Medicine and CHOP". FOX43. Retrieved August 21, 2024.
  47. ^ McGinley, Laurie (October 26, 2021). "FDA approves first gene therapy for an inherited disease". Washington Post. Retrieved August 21, 2024.
  48. ^ Scott, Maiken (November 27, 2023). "CHOP's on-site production could lower high cost of gene therapies". WHYY. Retrieved August 8, 2024.
  49. ^ Gantz, Sarah (November 28, 2023). "FDA is investigating whether CAR-T, a cancer therapy pioneered at Penn, can cause lymphoma". The Philadelphia Inquirer. Retrieved August 8, 2024.
  50. ^ "CAR T-Cell Therapy Performs Just as Well in Low-Income Kids as in Wealthier Kids". Inside Precision Medicine. November 16, 2022. Retrieved August 8, 2024.
  51. ^ "CAR T Cell Therapies Last Longer, Work Better with FOXO1 Protein". GEN - Genetic Engineering and Biotechnology News. April 11, 2024. Retrieved August 8, 2024.
  52. ^ Cohen, Jessica Kim (January 25, 2024). "Young Boy Can Hear After Receiving Eli Lilly's Gene Therapy, Bolstering Similar Programs". Precision Medicine Online. Retrieved August 22, 2024.
  53. ^ Grassi, Emily Rose (January 24, 2024). "Boy born deaf can hear for the first time thanks to ground-breaking gene therapy". NBC10 Philadelphia. Retrieved August 8, 2024.
  54. ^ Harder, Ben (16 June 2020). "The Honor Roll of U.S. News Best Children's Hospitals 2020-21". U.S. News & World Report. Archived from the original on 16 June 2020. Retrieved 16 June 2020.
  55. ^ Harder, Ben (October 8, 2024). "Best Children's Hospitals 2024-2025 Honor Roll and Overview". US News & World Report. Retrieved March 3, 2025.
  56. ^ "Children's Hospital of Philadelphia". U.S. News & World Report. Retrieved March 3, 2025.
  57. ^ a b Cite error: The named reference :3 was invoked but never defined (see the help page).

I know there's a lot here, so let me know if it makes more sense to break these out into separate items or if there's anything else I can do to make this easier to review. Thank you for your time! Mary Gaulke (talk) 21:00, 5 March 2025 (UTC)[reply]

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